CAT 2025 Set-3 | Verbal Ability and Reading Comprehension | Question: 2

Question

The given sentence is missing in the paragraph below. Decide where it best fits among the options $1, 2, 3$, or $4$ indicated in the paragraph.

Sentence: In each of the affected males, the genetic defect was located to the $\mathrm{X}$ chromosome in the region of $\mathrm{p}11-12$.

Paragraph: The first suggested evidence of a human genetic mutation associated with aggressive behaviour came from a study in $1993$. $\_\_\_\_ (1) \_\_\_\_$. Genetic and metabolic studies were conducted on a large Dutch family in which several of the males has a syndrome of borderline mental retardation and abnormal behaviour. $\_\_\_\_(2) \_\_\_\_$. The undesirable behaviour included impulsive aggression, arson and exhibitionism. $\_\_\_\_(3)\_\_\_\_$. A point mutation was identified in the eighth exon of the monoamine oxidase A (MAOA) structural gene which changes glutamine to a termination codon. $\_\_\_\_(4) \_\_\_\_$.

• A. Option $2$
• B. Option $3$
• C. Option $1$
• D. Option $4$