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A supplement of Vitamin A and Zinc may boost children's resistance to Malaria(observation from one experiment conducted in a village $’X'$). Which of the following, if true, would weaken the statement?

1. No adult in village $’X'$ has fallen sick because of Malaria.
2. For the last three years there is hardly any case of child affected by Malaria from village $’X'$.
3. The experiment with Vitamin A and Zinc is being duplicated in other nearby cities adjacent to village $’X'$.
4. Villages adjacent to $’X'$ have reported substantial cases of Malaria affecting mostly children.
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